Expert Insights Newsletter by Author

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Proton-pump Inhibitors - A Strategy For Reducing Inappropriate Use

Proton-pump inhibitors (PPIs) are the leading therapy for upper gastrointestinal disorders, but their overutilization and inappropriate use is exposing patients to a range of potential risks.1 Dr. Aamir Ali, Assistant Professor of Medicine, George Washington University, discusses the growing concern... Read more 

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The Use of Genetic Markers to Improve Outcomes in Non-Small Cell Lung Cancer

Despite advances in surgical technique and drug therapy, lung cancer remains as one of the leading causes of cancer-related deaths.1 While reductions in tobacco use provide the largest single opportunity for preventing deaths due to lung cancer­,2 recent developments in... Read more 

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Managing Chronic Pain - A Structured Approach for More Effective Patient Care

Chronic pain affects a significant proportion of adults in the United States ' over 100 million Americans according to recent estimates.1 This is more people than are affected by heart disease, diabetes, and cancer combined, yet chronic pain management and... Read more 

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Hepatitis C: How Broad Screening and New Therapies Can Transform the Disease Burden

Approximately 3.2 million people in the United States have chronic hepatitis C virus (HCV) infection, with infection most prevalent among those born during 1945'1965. Less than half of those with HCV have been diagnosed.1-3 To address the impact of this... Read more 

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Knowing the score: Identifying patients at high risk of liver fibrosis from Non-Alcoholic Fatty Liver Disease (NAFLD)

Non-alcoholic fatty liver disease (NAFLD) affects up to a third of the general population. Patients with its more severe form, nonalcoholic steatohepatitis (NASH), are at significant risk for developing end-stage liver disease. Strongly associated with obesity and type 2 diabetes,... Read more 

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Chikungunya: A Growing Public Health Concern for the United States

Last year, the Centers for Disease Control and Prevention (CDC) had warned that the number of chikungunya cases among travelers from affected areas was increasing and these imported cases could result in local spread of the virus in the continental... Read more 

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Familial Hypercholesterolemia — Managing a Potentially Devastating Disorder

Familial Hypercholesterolemia (FH) is a genetic disorder, which causes premature atherosclerotic cardiovascular disease, and can lead to serious cardiac events in young patients, even those under 10 years of age. Dr. Seth Baum, Medical Director, Women's Preventive Cardiology, Boca Raton... Read more 

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Current Issues and Hot Topics in HIV Treatment & Diagnostics

In January 2011, the U.S. Department of Health and Services (DHHS) published revised "Guidelines for the Use of Antiretroviral Agents in HIV-infected Adults and Adolescents." They offer a number of updates on important issues, including: Recommending early initiation of antiretroviral... Read more 

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Rheumatoid Arthritis and Psoriatic Arthritis: The Role of Laboratory Testing in Disease Management

The diagnosis of rheumatoid arthritis (RA) and psoriatic arthritis (PsA) is primarily based on clinical criteria, but laboratory testing plays an important role in helping define the disease and manage therapy. Dr. Martin Bergman, Clinical Associate Professor of Medicine, Drexel... Read more 

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Rheumatoid Arthritis — Intervening Early to Improve Outcomes

An estimated 1.5 million adults suffer from rheumatoid arthritis in the United States, with the incidence two to three times higher in women than men.1 It is a condition that significantly compromises quality of life, and can increase the risk... Read more 

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Aspirin Resistance

Approaches for Optimizing Anti-Platelet Therapy Daily intake of low dose aspirin (acetylsalicylic acid) has been established as the standard of care in managing cardiovascular disease in the U.S.1 While aspirin plays an important role in helping prevent cardiovascular events, a... Read more 

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A New Algorithm for HIV Laboratory Testing

The Centers for Disease Control and Prevention (CDC) has proposed a new algorithm for laboratory testing of human immunodeficiency virus (HIV) to replace the algorithm that has been recommended for over twenty years.1, 2 This is intended to address shortcomings... Read more 

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Meeting an Increased Demand for Laboratory Services as Healthcare Evolves

Increasing volumes, declining reimbursement and added cost pressures are just some of the challenges facing the hospital laboratory today. What strategies can laboratories pursue to meet these challenges and enhance the value they contribute to patient care and to their... Read more 

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Hepatitis — Diagnostic Advances Help Guide New Therapies

An estimated 4.4 million Americans are living with chronic hepatitis - the majority unaware they are infected. Approximately 30% have chronic Hepatitis B (HBV) infection, and 70% have chronic Hepatitis C (HCV). It is estimated that about 80,000 new infections... Read more 

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The Role of Interferon-Gamma Release Assays (IGRAs) in the Diagnosis of Tuberculosis

World TB Day, taking place on March 24, 2013, is an annual reminder of the global burden of tuberculosis (TB), raising awareness of efforts to control and prevent the disease.1 While TB mortality has fallen over 40% worldwide since 1990,... Read more 

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Vitamin D Testing — Increasing Accuracy, Improving Patient Management

The National Institutes of Health are in the process of establishing a standardized approach for vitamin D Testing. This promises to improve the detection, evaluation, and treatment of vitamin D deficiency and insufficiency by making measurements of serum total 25-hydroxyvitamin... Read more 

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Testosterone Measurement — Standardizing Testing to Increase Accuracy

Testosterone testing is utilized to diagnose and monitor a range of disorders in men, women and children but variability and inaccuracy often compromise testing reliability. Initiatives led by the Endocrine Society and the Centers for Disease Control and Prevention (CDC)... Read more 

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Allergic Disease

Strategies For Optimum Patient Management "Allergic disease is one of the most common and costly chronic diseases in both pediatrics and adults," says Dr. Linda Cox, Allergist in private practice in Ft. Lauderdale). "It's prevalent, it's rising and it represents... Read more