Webinars

Breakthroughs in Alzheimer’s Disease Assessment: Quantitation of CSF Beta Amyloid 40 & 42

Date: Wednesday, June 14, 2017

Author: Clarke, Nigel J., PhD
Senior Science Director for Mass Spectrometry and Automation
Quest Diagnostics Nichols Institute
San Juan Capistrano, CA

  
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Category: For Credit, Webinar

Description: Dr Clarke discusses the advantages in assessing Alzheimer’s disease by measurement of amyloid beta 42/40 ratio, describes an improved LC-MS/MS approach for quantitating amyloid beta and Apolipoprotein E phenotyping and its advantages over ELISA platforms, and reviews a new, comprehensive metric that assesses a patient’s overall risk of developing Alzheimer’s disease, represented by a total hazards ratio.

At the conclusion of this program, participants will be able to:
- Discuss the advantages in assessing Alzheimer’s disease risk by measurement of the amyloid beta 42/40 ratio
- Describe an improved LC-MS/MS approach for amyloid beta 42/40 quantitation and Apolipoprotein E phenotyping, and discuss the potential advantages of this approach relative to ELISA platforms
- Review a new, comprehensive “risk assessment score” used to assess a patient’s risk of having Alzheimer’s disease

ASCLS P.A.C.E.® credits are available to laboratory professionals through November 24, 2017.