Clinical Education Center

Authors: Gervais JR, Hobbs GA

Use of an acetyl derivative to improve GC-MS determination of norbuprenorphine in the presence of high concentrations of buprenorphine in the urine

Specialties: Toxicology/Pain Management

Quest Diagnostics Authors: Agersborg, S
Authors: Nassar A, Cohen C, Zhou W, Lynch KA, Heyman ER, Olson A, Lange H, Siddiqui MT.

A new immunohistochemical ER/PR image analysis system: a multisite performance study.

Specialties: Endocrinology, Diabetes & Metabolism, Oncology, Pathology, Laboratory Medicine, Women's Health/OB/GYN

Quest Diagnostics Authors: Agersborg, S
Authors: Nassar A, Cohen C, Zhou W, Lynch KA, Albitar M, Barker EA, Vanderbilt BL, Thompson J, Heyman ER, Lange H, Olson A, Siddiqui MT.

Trainable immunohistochemical HER2/neu image analysis: a multisite performance study using 260 breast tissue specimens.

Specialties: Infectious Disease, Oncologists, Pathologists, Pediatrics

Quest Diagnostics Authors: Agersborg, S
Authors: Nassar A, Cohen C, Albitar M, Zhou W, Lynch KA, Heyman ER, Lange H, Siddiqui MT.

Reading immunohistochemical slides on a computer monitor--a multisite performance study using 180 HER2-stained breast carcinomas.

Specialties: Internal Medicine, Oncologists, Pathologists, Women's Health/OB/GYN

Quest Diagnostics Authors: Agersborg, S
Authors: Nassar A, Cohen C, Zhou W, Lynch KA, Barker EA, Vanderbilt BL, Thompson J, Heyman ER, Olson A, Lange H, Siddiqui MT.

A multisite performance study comparing the reading of immunohistochemical slides on a computer monitor with conventional manual microscopy for estrogen and progesterone receptor analysis.

Specialties: Oncology, Pathology, Laboratory Medicine

Authors: Wang JC, Mahon LW, Ross LP, Anguiano A, Owen R, Boyar FZ

Enrichment of small pathogenic deletions at chromosome 9p24.3 and 9q34.3 involving DOCK8, KANK1, EHMT1 genes identified by using high-resolution oligonucleotide-single nucleotide polymorphism array analysis

Specialties: Genetics

Authors: Vasale J, Boyar F, Jocson M, Sulcova V, Chan P, Liaquat K, Hoffman C, Meservey M, Chang I, Tsao D, Hensley K, Liu Y, Owen R, Braastad C, Sun W, Walrafen P, Komatsu J, Wang JC, Bensimon A, Anguiano A, Jaremko M, Wang Z, Batish S, Strom C, Higgins J

Molecular combing compared to Southern blot for measuring D4Z4 contractions in FSHD

Specialties: Neurology

Quest Diagnostics Authors: Anguiano, A, Deming, A, Elnaggar, M, Hafezi, K, Hinman, L, Mahon, L, Ross, L, Sahoo, T, Wang, J
Authors: Sanchez-Lara P, Bruno Y, Bartley JA, Liehr T, Jones M

Concurrent triplication and uniparental isodisomy: evidence for microhomology-mediated break-induced replication model for genomic rearrangements.

Specialties: Genetics, Pathology, Laboratory Medicine

Quest Diagnostics Authors: Anguiano, A, Boyar, F, El, N, Haddadin, M, Hemmat, M, Kopita, A, Mahon, L, Owen, R, Ross, L, Sahoo, T, Strom, C, Wang, T, Wang, J
Authors: Randolph LM, Chase JM, Matas Aguilera MJ, Siles JL, Church JA, Hauser N, Shen JJ, Jones MC, Wierenga KJ, Jiang Z

Regions of homozygosity identified by oligonucleotide SNP arrays: evaluating the incidence and clinical utility.

Specialties: Genetics, Pulmonology, Women's Health/OB/GYN

Quest Diagnostics Authors: Arvai, K, Jones, D, Lee, L

Annotation of Sequence Variants in Cancer Samples: Processes and Pitfalls for Routine Assays in the Clinical Laboratory.

Specialties: Genetics, Oncology, Pathology, Laboratory Medicine

Authors: Li Y, Arellano AR, Bare LA, Bender RA, Strom CM, Devlin JJ

A Multigene Test Could Cost-Effectively Help Extend Life Expectancy for Women at Risk of Hereditary Breast Cancer.

Specialties: Clinical and Lab healthcare professionals, Genetics, Nurse practitioners, Oncology, Pathology, Laboratory Medicine, Women's Health/OB/GYN

Authors: Shiffman D, Arellano AR, Caulfield MP, Louie JZ, Bare LA, Devlin JJ, Melander O

Use of low density lipoprotein particle number levels as an aid in statin treatment decisions for intermediate risk patients: a cost-effectiveness analysis

Specialties: Cardiology, Endocrinology, Diabetes & Metabolism

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Authors: Shiffman D, Perez MV, Bare LA, Louie JZ, Arellano AR, Devlin JJ

Genetic risk for atrial fibrillation could motivate patient adherence to warfarin therapy: a cost effectiveness analysis.

Specialties: Cardiology, Genetics

Quest Diagnostics Authors: Bare, L, Bender, R, Devlin, J, Li, Y, Sninsky, J, Waldman, F
Authors: Wilson LS

Cost Effectiveness of Sequencing 34 Cancer-Associated Genes as an Aid for Treatment Selection in Patients with Metastatic Melanoma.

Specialties: Health Information Technology, Oncology, Women's Health/OB/GYN

Authors: Li Y, Bare LA, Bender RA, Sninsky JJ, Wilson LS, Devlin JJ, Waldman FM

Cost Effectiveness of Sequencing 34 Cancer-Associated Genes as an Aid for Treatment Selection in Patients with Metastatic Melanoma.

Specialties: Genetics, Oncology

Quest Diagnostics Authors: Batterman, HJ, Matud, J, Prince, H, Seaton, B

Chikungunya virus RNA and antibody testing at a National Reference Laboratory since the emergence of Chikungunya virus in the Americas.

Specialties: Infectious Disease, Pathology, Laboratory Medicine

Quest Diagnostics Authors: Bennet, J, Bowen, D, Cermcack, J
Authors: Della Porta MG, Tuechler H, Malcovati L, Schanz J, Sanz G, Garcia-Manero G, Sole F, Fenaux P, Dreyfus F, Kantarjian H, Kuendgen A, Levis A, Fonatsch C, Le Beau MM, Slovak ML, Krieger O, Luebbert M, Maciejewski J, Magalhaes SM, Miyazaki Y, Pfeilstocker M,

Validation of WHO classification-based Prognostic Scoring System (WPSS) for myelodysplastic syndromes and comparison with the revised International Prognostic Scoring System (IPSS-R). A study of the International Working Group for Prognosis in Myelodysplasia (IWG-PM)

Specialties: Health Information Technology, Hematology/Hemostasis/Thrombosis, Oncology

Quest Diagnostics Authors: Bi, C, Caston-Balderrama, A, Clarke, NJ, Garber, C, Kaufman, HW, Kroll, MH, Reitz, R, Suffin, S, Zhang, K
Authors: Liu D, Xie M, Holick MF

Temporal relationship between vitamin D status and parathyroid hormone in the United States.

Specialties: Endocrinology, Diabetes & Metabolism, General Health and Wellness, Internal Medicine, Toxicology/Pain Management

Quest Diagnostics Authors: Blatt, A, Kennedy, R, Luff, R, Rabin, D
Authors: Austin RM

Comparison of cervical cancer screening results among 256,648 women in multiple clinical practices.

Specialties: Genetics, Oncology, Pathology, Anatomic, Women's Health/OB/GYN

Quest Diagnostics Authors: Blochin, E, Elston, D
Authors: Kazlouskaya V, Krulig E, Fong D

Periorbital indurated lesions in a 67-year-old female patient.

Specialties: Dermatology, Oncology, Pathology, Laboratory Medicine, Women's Health/OB/GYN

Authors: Yu Y, Sikorski P, Smith M, Bowman-Gholston C, Cacciabeve N, Nelson KE, Pieper R.

Comprehensive Metaproteomic Analyses of Urine in the Presence and Absence of Neutrophil-Associated Inflammation in the Urinary Tract.

Specialties: Genetics, Urology

Quest Diagnostics Authors: Bowman-Gholston, C
Authors: Yu Y, Sikorski P, Cacciabeve N, Nelson KE, Pieper R

Diagnosing inflammation and infection in the urinary system via proteomics.

Specialties: Infectious Disease, Pathology, Laboratory Medicine, Urology

Authors: Wang JC, Boyar FZ

Chromosomal microarray analysis as the first-tier test for the identification of pathogenic copy number variants in chromosome 9 pericentric regions and its challenge.

Specialties: Genetics, Neurology, Pathology, Laboratory Medicine, Pediatrics

Authors:

Spectral karyotyping for identification of constitutional chromosomal abnormalities at a national reference laboratory.

Specialties: Pediatrics, Women's Health/OB/GYN

Authors: Strom CM, Anderson B, Tsao D1, Zhang K, Liu Y, Livingston K, Elzinga C2, Evans M, Nguyen Q, Wolfson D, Rowland C, Kolacki P, Maxwell M, Wang JC, Rabin D, Catanese J, Owen R, Braastad C, Sun W.

Improving the Positive Predictive Value of Non-Invasive Prenatal Screening (NIPS).

Specialties: Genetics, Women's Health/OB/GYN

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Authors: Iakoubova O, Tong C, Catanese J, Rowland C, Luke M, Tranquilli M, Elefteriades JA

KIF6 719Arg Genetic Variant and Risk for Thoracic Aortic Dissection

Specialties: Cardiology, Genetics

Quest Diagnostics Authors: Catanese, J, Li, Y
Authors: Yin X, Low HQ, Wang L, Ellinghaus E, Han J, Estivill X, Sun L, Padyukov L, Krueger GG, Duffin KC, Mucha S, Weichenthal M, Weidinger S, Lieb W, Foo JN, Sim K, Liany H, Irwan I, Teo Y, Theng CT, Gupta R, Bowcock A, De Jager PL, Qureshi AA, de Bakker PI, Se

Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility.

Specialties: Dermatology, Genetics, Internal Medicine

Authors: Lu Y, Zhou S, Dreyer RP, Caulfield M, Spatz ES, Geda M, Lorenze NP, Herbert P, D'Onofrio G, Jackson EA, Lichtman JH, Bueno H, Spertus JA, Krumholz HM

Sex Differences in Lipid Profiles and Treatment Utilization Among Young Adults With Acute Myocardial Infarction: Results from the VIRGO Study

Specialties: Cardiology, Endocrinology, Diabetes & Metabolism, Lipidology

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Authors: Mora S, Caulfield MP, Wohlgemuth J, Chen Z, Superko HR, Rowland CM, Glynn RJ, Ridker PM, Krauss RM

Atherogenic Lipoprotein Subfractions Determined by Ion Mobility and First Cardiovascular Events After Random Allocation to High-Intensity Statin or Placebo: The Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER) Trial.

Specialties: Cardiology, Endocrinology, Diabetes & Metabolism

Quest Diagnostics Authors: Caulfield, MP, Hantash, F
Authors: Abbasi F, Blasey C, Feldman D, Reaven GM

Low circulating 25-hydroxyvitamin D concentrations are associated with defects in insulin action and insulin secretion in persons with prediabetes.

Specialties: Cardiology, Endocrinology, Diabetes & Metabolism, Pathology, Laboratory Medicine

Quest Diagnostics Authors: Caulfield, MP, Hantash, F
Authors: Feldman D, Reaven GM

Relationship among 25-hydroxyvitamin D concentrations, insulin action, and cardiovascular disease risk in patients with essential hypertension.

Specialties: Cardiology, General Health and Wellness, Internal Medicine

Quest Diagnostics Authors: Caulfield, MP
Authors: Landenhed M, Engstrom G, Gottsater A, Hedblad B, Newton-Cheh C, Melander O, Smith JG

Risk profiles for aortic dissection and ruptured or surgically treated aneurysms: a prospective cohort study.

Specialties: Cardiology, Hematology/Hemostasis/Thrombosis, Transplant

Quest Diagnostics Authors: Caulfield, MP, Hantash, F
Authors: Seibert R, Abbasi F, Reaven G, Kim SH

Relationship between insulin resistance and amino acids in women and men.

Specialties: Endocrinology, Diabetes & Metabolism

Authors: Melander O, Shiffman D, Caulfield MP, Louie JZ, Rowland CM, Devlin JJ, Krauss RM.

Low-Density Lipoprotein Particle Number Is Associated With Cardiovascular Events Among Those Not Classified Into Statin Benefit Groups.

Specialties: Cardiology

Quest Diagnostics Authors: Caulfield, MP, Clarke, NJ, McPhaul, MJ, Reitz, R
Authors: Goldman, Mildred M. BS, CLS; Viec, Khanh V. BS;

The Measurement of 3-Epimer 25-Hydroxyvitamin D by Mass Spectrometry in Clinical Specimens Detects Inconsequential Levels in Adult Subjects

Specialties: Endocrinology, Diabetes & Metabolism, Endocrinology, Diabetes & Metabolism, General Health and Wellness, Internal Medicine, Pathology, Laboratory Medicine, Pediatrics

Authors: Kaufman H and Chen Z

Vitamin D Status and Supplementation in Employer-Sponsored Wellness Program

Specialties: Endocrinology, Diabetes & Metabolism

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Authors: Kaufman HW, Chen Z

Trends in Laboratory Rotavirus Detection: 2003 to 2014.

Specialties: Infectious Disease, Pathology, Laboratory Medicine, Pediatrics

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Quest Diagnostics Authors: Chen, Z, Kaufman, HW, McPhaul, MJ
Authors: Fonseca VA

Surge in newly identified diabetes among medicaid patients in 2014 within medicaid expansion States under the affordable care act.

Specialties: Endocrinology, Diabetes & Metabolism, Health Information Technology, Oncology

Quest Diagnostics Authors: Clarke, NJ
Authors: Simerman AA, Hill DL, Grogan TR, Elashoff D, Goldstein EH, Manrriquez AN, Chazenbalk GD, Dumesic DA

Intrafollicular cortisol levels inversely correlate with cumulus cell lipid content as a possible energy source during oocyte meiotic resumption in women undergoing ovarian stimulation for in vitro fertilization.

Specialties: Endocrinology, Diabetes & Metabolism, Women's Health/OB/GYN

Quest Diagnostics Authors: Clarke, NJ, Reitz, R
Authors: Toledo A, Amato CS, Salo D

Injectable dexamethasone sodium phosphate administered orally? A pharmacokinetic analysis of a common emergency department practice.

Specialties: Internal Medicine, Pathology, Laboratory Medicine, Pediatrics

Quest Diagnostics Authors: Clarke, NJ
Authors: Bystrom CE, Sheng S.

Narrow mass extraction of time-of-flight data for quantitative analysis of proteins: determination of insulin-like growth factor-1.

Specialties: Endocrinology, Diabetes & Metabolism, Pathology, Anatomic, Pathology, Laboratory Medicine

Quest Diagnostics Authors: Clarke, NJ
Authors: Hoofnagle AN.

Mass spectrometry continues its march into the clinical laboratory.

Specialties: Pathology, Anatomic, Pathology, Laboratory Medicine

Quest Diagnostics Authors: Cockerill, F
Authors: Lyon E, Bale SJ, Beadling C, Bry L, Hagenkord J, Kulkarni S, Press R, Palomaki GE

Next generation sequencing in clinical diagnostics: experiences of early adopters.

Specialties: Pathology, Laboratory Medicine

Quest Diagnostics Authors: Cohen, JR
Authors: Bronfenbrener R, Slutsky JB

Conflicting dermoscopic criteria in a suspicious lesion.

Specialties: Dermatology, Geriatrics/Age Management, Oncology, Pathology, Anatomic

Quest Diagnostics Authors: Cohen, JR

The health crises of chronic pain and prescription drug misuse.

Specialties: Pathology, Anatomic, Toxicology/Pain Management