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Clarke, Nigel J., PhD

Senior Science Director for Mass Spectrometry and Automation
Quest Diagnostics Nichols Institute
San Juan Capistrano, CA

Expert Insight: Innovations in Alzheimer’s Disease Assessment: Quantitation of Amyloid Beta 40 and 42

Expert Insight: Vitamin D Testing — Increasing Accuracy, Improving Patient Management

Expert Insight: Testosterone Measurement — Standardizing Testing to Increase Accuracy

Presentation: Alzheimer’s Disease: The Role of Amyloid Beta 42/40 in Risk Assessment

Presentation: Breakthroughs in Alzheimer’s Disease Assessment: Quantitation of CSF Beta Amyloid 40 & 42

Publication: Electrokinetic Mixing for Improving the Kinetics of an HbA1c Immunoassay.

Publication: High-Throughput Mass Spectrometry Assay for Quantifying β-Amyloid 40 and 42 in Cerebrospinal Fluid.

Publication: Measurement of Cortisol and Testosterone in Athletes: Accuracy of Liquid Chromatography-Tandem Mass Spectrometry Assays for Cortisol and Testosterone Measurement in Whole-Blood Microspecimens.

Publication: Total and free cortisol levels during 1 μg, 25 μg, and 250 μg cosyntropin stimulation tests compared to insulin tolerance test: results of a randomized, prospective, pilot study.

Publication: Temporal relationship between vitamin D status and parathyroid hormone in the United States.

Publication: Intrafollicular cortisol levels inversely correlate with cumulus cell lipid content as a possible energy source during oocyte meiotic resumption in women undergoing ovarian stimulation for in vitro fertilization.

Publication: Injectable dexamethasone sodium phosphate administered orally? A pharmacokinetic analysis of a common emergency department practice.

Publication: The Measurement of 3-Epimer 25-Hydroxyvitamin D by Mass Spectrometry in Clinical Specimens Detects Inconsequential Levels in Adult Subjects

Publication: Narrow mass extraction of time-of-flight data for quantitative analysis of proteins: determination of insulin-like growth factor-1.

Publication: Mass spectrometry continues its march into the clinical laboratory.