Expert Insights Newsletter

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Hepatitis C: How Broad Screening and New Therapies Can Transform the Disease Burden

Approximately 3.2 million people in the United States have chronic hepatitis C virus (HCV) infection, with infection most prevalent among those born during 1945'1965. Less than half of those with HCV have been diagnosed.1-3 To address the impact of this... Read more 

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Proton-pump Inhibitors - A Strategy For Reducing Inappropriate Use

Proton-pump inhibitors (PPIs) are the leading therapy for upper gastrointestinal disorders, but their overutilization and inappropriate use is exposing patients to a range of potential risks.1 Dr. Aamir Ali, Assistant Professor of Medicine, George Washington University, discusses the growing concern... Read more 

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Omega-3 and Omega-6 Fatty Acids — Measuring Blood Levels To Help Manage Cardiovascular Risk

While recommendations for dietary intake of omega-3 fatty acids to reduce cardiovascular disease risk are well established, debate continues about the benefits of omega-3 supplementation.1-4 Dr. Robert Superko, Chief Medical Officer, Celera, reviews the evidence relating to omega-3 intake and... Read more 

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Vaginitis — Molecular Testing To Address Diagnostic Challenges

Vaginitis is the most common gynecologic diagnosis in the primary care setting, affecting one in three women in their lifetime, but diagnosing its cause can be challenging.1 Dr. Dale Schwab, Senior Scientific Director, Infectious Disease, Quest Diagnostics Nichols Institute and... Read more 

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Rheumatoid Arthritis and Psoriatic Arthritis: The Role of Laboratory Testing in Disease Management

The diagnosis of rheumatoid arthritis (RA) and psoriatic arthritis (PsA) is primarily based on clinical criteria, but laboratory testing plays an important role in helping define the disease and manage therapy. Dr. Martin Bergman, Clinical Associate Professor of Medicine, Drexel... Read more 

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Epilepsy: How Next-Generation Genetic Testing Can Direct Therapy and Enhance Patient Care

Many types of epilepsy are associated with a genetic mutation, but determining the etiology of certain epilepsies remains a challenge. Dr. Scott Perry, Medical Director, Epilepsy Monitoring Unit, Cook Children's Health Care System, discusses how advances in genetic testing, including... Read more 

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BRCA Mutation Testing — Identifying Risk for Hereditary Breast and Ovarian Cancer

Compared to the general population, patients with a confirmed BRCA mutation have a significantly increased risk of developing cancer during their lifetime - up to an 85% risk of breast cancer, up to a 40% risk of ovarian cancer, and... Read more 

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Developmental Delay: Genetic Testing’s Role to Help Guide Diagnosis and Treatment

Causes of developmental delay are typically identified by a combination of observation, physical examination, assessment of family history and a range of diagnostic tests. For disorders of uncertain etiology, chromosomal microarray (CMA) testing provides clinicians with an additional diagnostic tool,... Read more 

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Vitamin D Testing — Increasing Accuracy, Improving Patient Management

The National Institutes of Health are in the process of establishing a standardized approach for vitamin D Testing. This promises to improve the detection, evaluation, and treatment of vitamin D deficiency and insufficiency by making measurements of serum total 25-hydroxyvitamin... Read more 

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A New Algorithm for HIV Laboratory Testing

The Centers for Disease Control and Prevention (CDC) has proposed a new algorithm for laboratory testing of human immunodeficiency virus (HIV) to replace the algorithm that has been recommended for over twenty years.1, 2 This is intended to address shortcomings... Read more