Expert Insights Newsletter

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Sex Hormone Measurement: How Evolving Technology Has Improved Test Accuracy, Precision and Reproducibility

For endocrinologists, laboratory testing is critical for patient diagnosis and monitoring, and assays for sex hormone measurement are at the core of endocrine practice. While the limitations of traditional direct immunoassays have been widely documented, test methodologies based on mass... Read more 

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Clostridium Difficile Infection — Addressing a National Epidemic

In recent years infections caused by Clostridium difficile (C. difficile) have reached epidemic levels in the United States, accounting for 250,000 illnesses per year and 14,000 deaths.1 Recognizing its link to antibiotic use, the Centers for Disease Control and Prevention... Read more 

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Cardiovascular Disease — A Comprehensive Approach to Manage the Risks of Cardiac Events

Lowering low-density lipoprotein cholesterol (LDL-C) is the primary target for cardiovascular disease (CVD) risk reduction and can significantly reduce the incidence of cardiovascular (CV) events.1 The latest guidelines, released November 2013, reiterate the need to continue to use evidence-based medicine... Read more 

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Hepatitis C — The Primary Care Physician’s Role in Reducing the Epidemic’s Impact

Hepatitis C virus (HCV) infection is the most common chronic blood borne infection in the United States affecting approximately 3.2 million people. The majority are asymptomatic and remain undiagnosed for many years but 60%-70% develop chronic liver disease due to... Read more 

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Helicobacter pylori Infection — Testing Options for Accurate Diagnosis and Management

Helicobacter pylori (H pylori) infection is extremely widespread, affecting approximately 50 percent of the world's population.1 While the overall prevalence in the United States is about 30%, prevalence in non-Hispanic blacks and Hispanic-Americans is 50% to 60%.2 Among immigrant groups... Read more 

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Vitamin D Deficiency — Identifying and Managing At-Risk Patients

National data demonstrate a marked decrease in vitamin D levels in the U.S. population over recent decades, prompting the assessment that we are facing a growing epidemic of vitamin D insufficiency.1 With the onset of Fall, and hours of sunlight... Read more 

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Ion Mobility: Question and Answer Session with the Experts

Question: What is the relationship between lipid regions separated by Ion Mobility and those on traditional gradient gel electrophoresis? Robert Superko, MD: Well, let me ask Ron to comment because he's the individual who developed both of those techniques. Ronald... Read more 

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Advanced Lipid Testing: Enabling a More Accurate Assessment of Cardiovascular Disease Risk

Cardiovascular disease (CVD) is the leading cause of death for both men and women in the U.S. accounting for one in three (approximately 800,000) deaths each year.1 Strategies to reduce the burden of CVD focus on the three leading risk... Read more 

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HIV Management — The Evolving Role of the Primary Care Physician

The recommendation for universal screening of adolescents and adults aged 15 to 65 years for HIV infection, issued by the United States Preventive Services Task Force (USPSTF) in April 2013,1 highlights the growing role for primary care physicians (PCPs) in... Read more 

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Allergic Disease — The Challenge of Recognition and Diagnosis

50 million people in the United States - 1 in 5 Americans ' suffer from allergy. It is the 5th leading chronic disease in the U.S. and the 3rd most common disease among children under 18 years old of age.1... Read more