Expert Insights Newsletter

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Prostate Cancer: Current Considerations for Screening and Treatment

Prostate cancer is the second-leading cause of cancer death in men in the United States, accounting for nearly 30,000 deaths per year.1 Incidence of prostate cancer peaked in the early 1990s, corresponding to the increased use of PSA testing for... Read more 

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The Use of Genetic Markers to Improve Outcomes in Non-Small Cell Lung Cancer

Despite advances in surgical technique and drug therapy, lung cancer remains as one of the leading causes of cancer-related deaths.1 While reductions in tobacco use provide the largest single opportunity for preventing deaths due to lung cancer­,2 recent developments in... Read more 

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Rheumatoid Arthritis — Intervening Early to Improve Outcomes

An estimated 1.5 million adults suffer from rheumatoid arthritis in the United States, with the incidence two to three times higher in women than men.1 It is a condition that significantly compromises quality of life, and can increase the risk... Read more 

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Chronic Myelogenous Leukemia: Testing to Detect and Treat Imatinib Resistance

The introduction of imatinib (Gleevec®) in 2001 dramatically improved the prognosis of patients with Chronic Myelogenous Leukemia (CML). An important aspect of therapy is the regular monitoring of patient response to identify those patients who are resistant, or become resistant,... Read more 

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Meeting an Increased Demand for Laboratory Services as Healthcare Evolves

Increasing volumes, declining reimbursement and added cost pressures are just some of the challenges facing the hospital laboratory today. What strategies can laboratories pursue to meet these challenges and enhance the value they contribute to patient care and to their... Read more 

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Testosterone Measurement — Standardizing Testing to Increase Accuracy

Testosterone testing is utilized to diagnose and monitor a range of disorders in men, women and children but variability and inaccuracy often compromise testing reliability. Initiatives led by the Endocrine Society and the Centers for Disease Control and Prevention (CDC)... Read more 

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Pain Medication - The Role of Genetic Variation in Drug Metabolism

Despite the widespread use of pain medications in the United States, there is little understanding among both physicians and patients about the potential variability in response to drugs commonly used for pain management. Dr Leland McClure, Director of Pain Management,... Read more 

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Managing Chronic Pain - A Structured Approach for More Effective Patient Care

Chronic pain affects a significant proportion of adults in the United States ' over 100 million Americans according to recent estimates.1 This is more people than are affected by heart disease, diabetes, and cancer combined, yet chronic pain management and... Read more 

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Sexually Transmitted Infections (STIs): Advances in Testing Technology

Sexually Transmitted Infections (STIs) are a significant public health concern in the United States - chlamydia and gonorrhea are the two most commonly reported notifiable diseases in the country.1 Edward (Ned) Hook, M.D., Director, Division of Infectious Diseases, Department of... Read more 

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Lung Cancer Testing: Why FISH for ALK Testing in NSCLC?

Last year the National Comprehensive Cancer Network (NCCN)1 and the American Society of Clinical Oncology (ASCO)2 issued recommendations for performing gene mutation testing to direct therapy for patients with non-small cell lung carcinoma (NSCLC). Dr. Aurelia Meloni-Ehrig, Chief Director, Cytogenetics,... Read more