Expert Insights Newsletter

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Cell-free Fetal DNA Testing - The Benefits of Accurate Non-Invasive Prenatal Testing

The use of maternal serum screening has become standard practice to identify women at risk of having a fetus with chromosomal abnormalities. Screening identifies 80%-90% of affected pregnancies but its specificity is very low ' only 5% of those screened... Read more 

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14-3-3eta (η) Protein — A New Biomarker for Rheumatoid Arthritis

An estimated 1.5 million adults suffer from rheumatoid arthritis in the United States, with the incidence two to three times higher in women than men.1 It is a condition that significantly compromises quality of life, and can increase the risk... Read more 

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The Role of Interferon-Gamma Release Assays (IGRAs) in the Diagnosis of Tuberculosis

World TB Day, taking place on March 24, 2013, is an annual reminder of the global burden of tuberculosis (TB), raising awareness of efforts to control and prevent the disease.1 While TB mortality has fallen over 40% worldwide since 1990,... Read more 

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Hepatitis C — A Review of the CDC Recommendations for Birth-Cohort Screening

The hepatitis C virus (HCV) is a serious public health concern, with an estimated 2.7 ' 3.9 million people living with infection in the United States1, where it is the leading cause of chronic liver disease. The prevalence of HCV... Read more 

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HIV Testing — Genotypic Technology in Tropism and Drug Resistance Testing

HIV tropism is defined as the cell type that HIV is able to enter and infect. The identification that HIV frequently uses the CCR5 co-receptor for cell entry led to the introduction of a class of HIV drugs called the... Read more 

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Kidney Stones — Understanding Risk, Reducing Recurrence

Kidney stone disease, also known as nephrolithiasis or urolithiasisis, is one of the most painful and prevalent urological disorders. Each year in the United States, kidney stones account for approximately three million visits to health care providers, and for over... Read more