Updates on the Clinical Utility of CCR5 Antagonists and HIV Tropism Testing
Description: Jonathan Z. Li, MD of Harvard Medical School and Brigham and Women’s Hospital discusses CCR5 antagonist therapy and the latest advances in genotypic testing using deep gene sequencing to identify HIV tropism. ASCLS P.A.C.E. credits available to laboratory professionals through August 19, 2013.
• Describe the importance of the CCR5 receptor for HIV-1 entry
• Characterize the clinical studies supporting the use of the CCR5 antagonist maraviroc
• Describe the tropism assays available to evaluate the appropriateness of CCR5 antagonist therapy
• Discuss novel CCR5 antagonists currently undergoing in clinical trials