Clinical Education Center

Immunotherapy- (Blinatumomab-) Related Lineage Switch of KMT2A/AFF1 Rearranged B-Lymphoblastic Leukemia into Acute Myeloid Leukemia/Myeloid Sarcoma and Subsequently into B/Myeloid Mixed Phenotype Acute Leukemia.

Authors: He RR, Nayer Z, Hogan M, Cuevo RS, Woodward K, Heyer D, Curtis CA, Peterson JF.
Case Rep Hematol. 2019 Dec 7;2019:7394619.

Specialties: Oncology

Genetic disruption of KCC cotransporters in a mouse model of thalassemia intermedia.

Authors: Shmukler BE, Rivera A, Bhargava P, Nishimura K, Kim EH, Hsu A, Wohlgemuth JG, Morton J, Snyder LM, De Franceschi L, Rust MB, Hubner CA, Brugnara C, Alper SL.
Blood Cells Mol Dis. 2019 Nov 25;81:102389.

Specialties: Oncology

SATB2 Protein Expression by Immunohistochemistry is a Sensitive and Specific Marker of Appendiceal and Rectosigmoid Well Differentiated Neuroendocrine Tumors.

Authors: Hoskoppal D, Epstein JI, Gown AM, Arnold Egloff SA, Gordetsky J, Shi CC, Giannico GA.
Histopathology. 2019 Oct 9. doi: 10.1111/his.14012. [Epub ahead of print]

Specialties: Oncology

Quantitative assessment of PD-L1 as an analyte in immunohistochemistry diagnostic assays using a standardized cell line tissue microarray

Authors: Martinez-Morilla S, McGuire J, Gaule P, Moore L, Acs B, Cougot D, Gown AM, Yaziji H, Wang WL, Cartun RW, Hornick JL, Sholl LM, Qiu J, Mino-Kenudson M, Yi ES, Beasley MB, Merrick DT, Ambaye AB, Zhang ZJ, Walker J, Rimm DL.
Lab Invest. 2019 Aug 13. doi: 10.1038/s41374-019-0295-9. [Epub ahead of print]

Specialties: Oncology

Pancreatic neuroendocrine microadenomatosis presenting as a functional VIPoma.

Authors: Krainev AA, Mathavan VK, Klink DF, Saxe JM, Ong GKB, Murphy JK.
J Surg Case Rep. 2019 Jun 28;2019(6):rjz196.

Specialties: Dermatology, Endocrinology, Diabetes & Metabolism, Gastroenterology, Oncology

Disclaimer: One or more of the authors of this publication were employed at the time by AmeriPath, a subsidiary of Quest Diagnostics.

Therapeutic plasma exchange for management of heparin-induced thrombocytopenia: Results of an international practice survey.

Authors: Onwuemene OA, Zantek ND, Rollins-Raval MA, Raval JS, Kiss JE, Ipe TS, Kuchibhatla M, Pagano MB, Wong ECC
J Clin Apher 2019 May 22. doi: 10.1002/jca.21709. [Epub ahead of print]

Specialties: Hematology/Hemostasis/Thrombosis, Oncology

Multiple immune suppressive mechanisms in fibrolamellar carcinoma.

Authors: Kim AK, Gani F, Layman AJ, Besharati S, Zhu Q, Succaria F, Engle EL, Bhaijee F, Goggins MB, Llosa NJ, Pawlik TM, Yarchoan M, Jaffee EM, Simons HC, Taube JM, Anders R.
Cancer Immunol Res. 2019 Mar;doi: 10.1158/2326-6066.CIR-18-0499. [Epub ahead of print]

Specialties: Dermatology, Gastroenterology, Oncology

Disclaimer: One or more of the authors of this publication were employed at the time by AmeriPath, a subsidiary of Quest Diagnostics.

Rare presentation of renal cell cancer as dysphagia: a case report.

Authors: Padda MS, Si WM.
J Med Case Rep. 2019 Mar;13(1):89. doi: 10.1186/s13256-018-1967-6.

Specialties: Gastroenterology, Oncology, Pathology

Disclaimer: One or more of the authors of this publication were employed at the time by AmeriPath, a subsidiary of Quest Diagnostics.

Newborn Screening for Severe Combined Immunodeficiency and T-cell Lymphopenia in California, 2010-2017.

Authors: Amatuni GS, Currier RJ, Church JA, Bishop T, Grimbacher E, Nguyen AA, Agarwal-Hashmi R, Aznar CP, Butte MJ, Cowan MJ, Dorsey MJ, Dvorak CC, Kapoor N, Kohn DB, Markert ML, Moore TB, Naides SJ, Sciortino S, Feuchtbaum L, Koupaei RA, Puck JM.
Pediatrics. 2019 Jan 25: doi: 10.1542/peds.2018-2300. [Epub ahead of print]

Specialties: Infectious Disease, Oncology, Pediatrics

Elderly do benefit from induction chemotherapy: High dose mitoxantrone-based ("5 + 1") induction chemotherapy regimen in newly diagnosed acute myeloid leukemia.

Authors: Saini NY, Cerny J, Furtado VF, Desmond A, Zhou Z, Raffel G, Puthawala I, Bednarik J, Shanahan L, Miron PM, Woda B, Ramanathan M, Nath R.
Am J Hematol. 2019 Feb;94:209-215.

Specialties: Geriatrics/Age Management, Oncology