Testing a panel of 12 single-nucleotide polymorphisms may help identify people at increased risk of atrial fibrillation and stroke, according to a recent study by researchers from the Lund University in Malmö, Sweden, the Broad Institute, Harvard Medical School, Cambridge, MA, and Quest Diagnostics. The award-winning poster may be accessed by ACC attendees through the ACC.14 Attendee Portal.
Compared to the general population, a woman with a confirmed BRCA1 or BRCA2 mutation is at greater risk of developing cancer during her lifetime—up to an 85% risk of breast cancer and up to a 40% risk of ovarian cancer. Her children, siblings and parents have a 50% chance of having the same autosomal dominant mutation and facing comparable risks.
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The immediate past chair of the U.S. Preventive Services Task Force, Michael L. LeFevre, MD, MSPH, explains the role and processes of the U.S. Preventive... Read more
Dr. Levenson helps attendees understand the potential factors causing inflammation, reviews the critical risk factors that can lead to inflammation and discusses the biomarkers and... Read more
Gerard Abate, MD, Quest Diagnostics medical director discusses the impact of personalized medicine on cardiovascular diagnostics. Read more
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Knowing the score: Identifying patients at high risk of liver fibrosis from Non-Alcoholic Fatty Liver Disease (NAFLD)
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Nassar A, Cohen C, Zhou W, Lynch KA, Barker EA, Vanderbilt BL, Thompson J, Heyman ER, Olson A, Lange H, Siddiqui MT.Bystrom CE.
Clin Chem. 2011;57:1091-1092.
'Criteria' aPL tests: report of a task force and preconference workshop at the 13th International Congress on Antiphospholipid Antibodies, Galveston, Texas, April 2010.
Nassar A, Cohen C, Zhou W, Lynch KA, Barker EA, Vanderbilt BL, Thompson J, Heyman ER, Olson A, Lange H, Siddiqui MT.Pierangeli SS, de Groot PG, Dlott J, Favaloro E, Harris EN, Lakos G, Ortel T, Meroni PL, Otomo K, Pengo V, Tincani A, Wong R, Roubey R.
Nassar A, Cohen C, Zhou W, Lynch KA, Barker EA, Vanderbilt BL, Thompson J, Heyman ER, Olson A, Lange H, Siddiqui MT.Ekins S, Litterman NK, Arnold RJ, Burgess RW, Freundlich JS, Gray SJ, Langley B, Willis DE, Notterpek L, Pleasure D, Sereda MW
A multisite performance study comparing the reading of immunohistochemical slides on a computer monitor with conventional manual microscopy for estrogen and progesterone receptor analysis.
Am J Clin Pathol. 2011;135:461-467.
Appl Immunohistochem Mol Morphol. 2011;19:195-202.