Expert Insights Newsletter by Author

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Hepatitis C — The Primary Care Physician’s Role in Reducing the Epidemic’s Impact

Hepatitis C virus (HCV) infection is the most common chronic blood borne infection in the United States affecting approximately 3.2 million people. The majority are asymptomatic and remain undiagnosed for many years but 60%-70% develop chronic liver disease due to... Read more 

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HIV Management — The Evolving Role of the Primary Care Physician

The recommendation for universal screening of adolescents and adults aged 15 to 65 years for HIV infection, issued by the United States Preventive Services Task Force (USPSTF) in April 2013,1 highlights the growing role for primary care physicians (PCPs) in... Read more 

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Vaginitis — Molecular Testing To Address Diagnostic Challenges

Vaginitis is the most common gynecologic diagnosis in the primary care setting, affecting one in three women in their lifetime, but diagnosing its cause can be challenging.1 Dr. Dale Schwab, Senior Scientific Director, Infectious Disease, Quest Diagnostics Nichols Institute and... Read more 

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Colorectal Cancer — Developments in Screening and Detection

Colorectal cancer (CRC) is the fourth most common cancer among men and women and the second leading cause of cancer deaths. Screening is highly effective at reducing the incidence and mortality of colorectal cancer, yet a significant proportion of the... Read more 

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Clostridium Difficile Infection — Addressing a National Epidemic

In recent years infections caused by Clostridium difficile (C. difficile) have reached epidemic levels in the United States, accounting for 250,000 illnesses per year and 14,000 deaths.1 Recognizing its link to antibiotic use, the Centers for Disease Control and Prevention... Read more 

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Helicobacter pylori Infection — Testing Options for Accurate Diagnosis and Management

Helicobacter pylori (H pylori) infection is extremely widespread, affecting approximately 50 percent of the world's population.1 While the overall prevalence in the United States is about 30%, prevalence in non-Hispanic blacks and Hispanic-Americans is 50% to 60%.2 Among immigrant groups... Read more 

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Cell-free Fetal DNA Testing - The Benefits of Accurate Non-Invasive Prenatal Testing

The use of maternal serum screening has become standard practice to identify women at risk of having a fetus with chromosomal abnormalities. Screening identifies 80%-90% of affected pregnancies but its specificity is very low ' only 5% of those screened... Read more 

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Solid Organ Transplantation - Toward More Individualized, Proactive Patient Management

There are numerous challenges to achieving successful organ transplantation. Dr. Terry Strom, Director, Transplant Research Center, Beth Israel Deaconess Medical Center, discusses how more precise patient monitoring following transplantation could provide the basis for more individualized, and more proactive, therapy.... Read more 

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Prescription Drug Abuse: Stemming the Tide of a New Epidemic

According to Robert Stutman, former special agent in the U.S. Drug Enforcement Agency (DEA) and one of the nation's top experts on drug abuse, we are in the midst of the worst drug epidemic seen in the U.S. in the... Read more 

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Omega-3 and Omega-6 Fatty Acids — Measuring Blood Levels To Help Manage Cardiovascular Risk

While recommendations for dietary intake of omega-3 fatty acids to reduce cardiovascular disease risk are well established, debate continues about the benefits of omega-3 supplementation.1-4 Dr. Robert Superko, Chief Medical Officer, Celera, reviews the evidence relating to omega-3 intake and... Read more 

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Ion Mobility: Question and Answer Session with the Experts

Question: What is the relationship between lipid regions separated by Ion Mobility and those on traditional gradient gel electrophoresis? Robert Superko, MD: Well, let me ask Ron to comment because he's the individual who developed both of those techniques. Ronald... Read more 

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Sex Hormone Measurement: How Evolving Technology Has Improved Test Accuracy, Precision and Reproducibility

For endocrinologists, laboratory testing is critical for patient diagnosis and monitoring, and assays for sex hormone measurement are at the core of endocrine practice. While the limitations of traditional direct immunoassays have been widely documented, test methodologies based on mass... Read more 

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Vitamin D Deficiency — Identifying and Managing At-Risk Patients

National data demonstrate a marked decrease in vitamin D levels in the U.S. population over recent decades, prompting the assessment that we are facing a growing epidemic of vitamin D insufficiency.1 With the onset of Fall, and hours of sunlight... Read more