What Pediatric Patients Need From Their Labs: Reference Ranges and Low-Volume Sample Handling
Date: Wednesday, November 30, 2011
Author: Nakamoto, Jon M., MD, PhD
Laboratory Medical Director
Quest Diagnostics Nichols Institute, San Juan Capistrano, CA
Associate Professor (Voluntary) of Pediatrics and Endocrinology
University of California, San Diego
Description: Jon Nakamoto, MD, PhD, Laboratory Medical Director for the Quest Diagnostics Nichols Institute in San Juan Capistrano, CA, and a pediatric endocrinology by training, discusses several of the key differences between diagnostic testing for adult and pediatric patients, including reference ranges, specimen requirements and more.
o Define "observed ranges," "reference intervals (reference ranges)," and "clinical thresholds"
o Outline the typical process by which reference intervals (reference ranges) are generated
o Discuss at least three major obstacles facing those who wish to generate accurate pediatric reference intervals
o Describe how mutual discussions between clinical laboratory experts and clinicians can be critical to obtain truly useful reference intervals